5 edition of Fluid and Solute Transport in the Airspace of the Lungs (Lung Biology in Health and Disease) found in the catalog.
January 15, 1994
by Informa Healthcare
Written in English
|The Physical Object|
|Number of Pages||539|
Fluid and solute resorption from the alveolus is critical in clearing ﬂuid from lungs at birth and in pathologic conditions, such as lung injury or acute respiratory distress syndrome, hydrostatic pulmonary edema, infant respiratory distress syn-drome, and reperfusion injury after lung transplantation. Active. The major principles governing solute and fluid transport across the peritoneal membrane are diffusion, driven by concentration gradients, and convection (filtration or UF), driven by osmotic or hydrostatic pressure gradients.
Fluid and solute reabsorption from the alveolus is critical in clearing fluid from lungs in pathologic conditions, such as acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) and. lung Introduction The movement of water between the airspace and blood com-partments of the lung is a developmentally and hormonally regulated process. During prenatal intrauterine life, the lungs remain filled by the continuous secretion of fluid whose com-position is distinctly different from plasma and amniotic fluid (1).
The mass movement of fluids into and out of capillary beds requires a transport mechanism far more efficient than mere diffusion. This movement, often referred to as bulk flow, involves two pressure-driven mechanisms: Volumes of fluid move from an area of higher pressure in a capillary bed to an area of lower pressure in the tissues via. COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.
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Fluid and Solute Transport in the AirsPates of the Lungs (Lung Biology in Health and Disease): Medicine & Health Science Books @ Presents cellular and clinical studies of solute and water transport across the distal membranes of the lungs, detailing selective and non-selective solute diffusion.
The work investigates evidence of active movement in preparations including whole lungs, isolated cells and cell membranes.
Fluid mechanical problems in the lung are unique. There is the matched distribution of two fluids, gas and blood, in two beautifully intertwined, branched conduit systems.
The reversing flow of the gas phase presents different problems than the pulsatile flow of the non-Newtonian fluid that is the blood. The sodium transport that drives water resorption in lung epithelia is predominantly limited by the epithelial sodium channel (ENaC) [ 35] whereas the Cl − transport that drives fluid secretion is maintained by different anion channels, most importantly the cystic fibrosis transmembrane conductance regulator (CFTR) Cited by: 1.
Both broad and deep in coverage, Rubenstein shows that fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement and renal transport. Each section initiates discussion with governing equations, derives the state equations and then shows examples of their usage.
Several drug transporters of the solute carrier (SLC and SLCO) and ATP binding cassette (ABC) families are expressed in the lung, and it is now known that active transport processes may affect the. Why is gas exchange more difficult for aquatic animals with gills than for terrestrial animals with lungs.
Water is less dense than air. Gills allow only unidirectional transport c. Gills allow water to flow in one direction d. Gills have less surface area than lungs. Water contains much less O2 than air.
Figure – Fluid Compartments in the Human Body: The intracellular fluid (ICF) is the fluid within cells. The interstitial fluid (IF) is part of the extracellular fluid (ECF) between the cells. Blood plasma is the second part of the ECF. Materials travel between cells and the plasma in capillaries through the IF.
A) movement of air into and out of the lungs. B) diffusion of gases between the interstitial fluid and the external environment. C) exchange of dissolved gases between the cells and interstitial fluids. D) binding of oxygen by hemoglobin.
E) utilization of oxygen by tissues to support metabolism. Glucose removal was inhibited by phloridzin but not by phloretin or by inhibiting glycolysis. The steady-state concentration in fluid-filled lungs was estimated to be +/- mM. It agreed with that (transport kinetics and paracellular permeability.
Purchase Renal Physiology - 5th Edition. Print Book & E-Book. ISBNBoth broad and deep in coverage, Rubenstein shows that fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement and renal transport.
Each section initiates discussion with governing equations, derives the state equations and then shows examples of their s: 1. Airspace T 3 rapidly restores the decreased alveolar fluid clearance in rat lungs with hyperoxia-induced lung injury.
Fluid and solute resorption from the alveolus is critical in clearing fluid from lungs at birth and in pathologic conditions, such as lung injury or acute respiratory distress syndrome, hydrostatic pulmonary edema, infant respiratory distress syndrome, and reperfusion injury Cited by: The active absorption of fluid from the airspaces of the lung is important for the resolution of clinical pulmonary edema.
Although ENaC channels provide a major route for Na + absorption, the route of Cl − transport has been unclear. We applied a series of complementary approaches to define the role of Cl − transport in fluid clearance in the distal airspaces of the intact mouse lung Cited by: The updated 2nd edition of this accessible and in-depth resource firmly relates molecular and cellular biology to the study of human physiology and disease.
Leading physiologists present you with practical, accurate coverage, continually emphasizing the clinical implications of the material. Each chapter explains the principles and organization of each body system, while more than high 5/5(1).
Ion and vectorial fluid transport in the lung is mediated by active transport of sodium (and chloride under cAMP stimulated conditions).
Sodium transport can be regulated by modulating either the activity (direct modulation of channel activity, channel Cited by: The major principles governing solute and fluid transport across the peritoneal membrane are diffusion, driven by concentration gradients, and convection (filtration or UF), driven by osmotic or hydrostatic pressure gradients.
The barrier separating the plasma in the peritoneal capillaries from the fluid in the peritoneal cavity is represented by the capillary wall and the interstitium. Purchase Biofluid Mechanics - 1st Edition.
Print Book & E-Book. ISBNBook Edition: 1. fluid transport across cellular barriers in biological tissues results from water transport driven by osmotic gradients or hydrostatic pressure differences. In the lung and airways, fluid movement between the air space and cellular and/or interstitial and vascular compartments is important in the maintenance of air space hydration, the absorption of air space fluid near the time of birth and.
In situ and isolated fluid-filled rabbit lungs were used to study the transport of indicators between the air space and vascular compartments. These indicators were placed in either the perfusate or air spaces and samples were collected from the perfusate at intervals during a 1-h perfusion period.
It is believed that high lung water permeability facilitates fluid absorption in the perinatal lung and airspace hydration in the adult lung, as well as the formation and resolution of pulmonary edema (8, 9).Fluid Reabsorption and Glucose Consumption in Edematous Rat Lungs Richard M.
Effros, Gregory R. Mason, K. Sietsema, P. Silverman, and J. Hukkanen Solute and water uptake were studied in isolated perfused rat lungs with airspaces filled with the perfusion fluid.
The albumin in this solution was labelled with Evans blue (T), and uptake of.Illuminates recent breakthroughs in understanding the pathogenesis & pathophysiology of pulmonary edema, & highlights new therapeutic options for managing patients with accompanying acute respiratory failure. Reviews state-of-the-art technology for measuring transvascular fluid flux & protein flux in the lung.